
In fact, countries where garlic is consumed in higher amounts, due to traditional cuisine, have been found to have a lower prevalence of cancer. Animal studies, and some early investigational studies in humans, have suggested possible cardiovascular benefits of garlic.
A Czech study found that garlic supplementation reduced accumulation of cholesterol on the vascular walls of animals.Another study had similar results, with garlic supplementation significantly reducing aortic plaque deposits of cholesterol-fed rabbits.
Another study showed that supplementation with garlic extract inhibited vascular calcification in human patients with high blood cholesterol.
The known vasodilative effect of garlic is possibly caused by catabolism of garlic-derived polysulfides to hydrogen sulfide in red blood cells, a reaction that is dependent on reduced thiols in or on the RBC membrane.
Hydrogen sulfide is an endogenous cardioprotective vascular cell-signaling molecule.
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